First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group.
Crebbin K, Mitford E, Paxton R, Turkington D
Northumberland, Tyne and Wear NHS Trust, Northumberland, UK.
BACKGROUND: Little is known about first-episode drug-induced psychosis (F19.5). OBJECTIVES: To examine the incidence, course, diagnostic stability, and outcomes of first-episode drug-induced psychosis (F19.5), and compare with first-episode schizophrenia (F20-21). METHOD: An observational database was set up on all patients aged 16 and over with a first episode psychosis living in a county in Northern England between October 1998 and October 2005. Data were collected at presentation and annual follow-up. Information on patients with an ICD-10 diagnosis of either drug-induced psychosis (F19.5) or schizophrenia (F20) was compared. RESULTS: There was no significant difference between the two groups in levels of hospitalisation and violence. Patients with a drug-induced psychosis were more likely to lose contact with services, and a third developed a schizophrenia-spectrum disorder. CONCLUSIONS: Increased attention should be paid to maintaining engagement with this high-risk group who have a high rate of transition to schizophrenia.
Published 28 August 2009 in Soc Psychiatry Psychiatr Epidemiol, 44(9): 710-5.
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